The Scoville scale is a measure of spiciness, which is based on the concentration of capsaicin in a substance - the compound that makes peppers hot. They have an average rating of 1,641,183 Scoville heat units (SHU) with some individual Carolina Reapers as high as 2.2 million SHU. Since 2013, Carolina Reapers have held the Guinness World Record for the world's hottest chili pepper. So in addition to making your mouth burn and turning you into a teary-eyed, snotty mess, extremely hot peppers may have more serious health consequences. Given that the man developed the symptoms after consuming a vasoactive substance, the doctors concluded that eating the Carolina Reaper could have been the reason he developed RCVS. So in other words, hot peppers are known to have vasoactive properties, meaning that they can affect the size of blood vessels. However, eating cayenne pepper has been linked to heart attacks and a narrowing of the blood vessels in the heart, known as coronary vasospasm, according to the report. There have been no known cases of RCVS associated with hot peppers. However, some people can develop brain damage. People with RCVS require supportive care like fluids and rest, and the condition typically goes away on its own within days to weeks. Satish Boddhula of Bassett Medical Center in Cooperstown, New York, and colleagues. However, the man tested negative for those and had no significant medical history or conditions that could explain his reaction, according to study author Dr. ![]() It's not always clear what causes RCVS, but it can sometimes be due to unusual reactions to medications like serotonin reuptake inhibitors (which are antidepressants like Prozac or Zoloft) or illicit drugs such as cocaine or amphetamines. ![]() The main symptom of RCVS is a thunderclap headache. This rare condition is caused by the sudden narrowing of the major blood vessels in the brain.
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